Kyle J MacBeth Selected Research

enasidenib

1/2022	Enasidenib-induced differentiation promotes sensitivity to venetoclax in IDH2-mutated acute myeloid leukemia.
1/2021	Combination of azacitidine and enasidenib enhances leukemic cell differentiation and cooperatively hypomethylates DNA.
4/2020	Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.
11/2019	Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.
1/2019	Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

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Kyle J MacBeth Research Topics

Disease

9	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021 - 01/2010
7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 02/2010
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 01/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 01/2010
2	Neoplasms (Cancer) 12/2018 - 01/2010
1	Carcinogenesis 12/2018
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2015

Drug/Important Bio-Agent (IBA)

5	enasidenibIBA 01/2022 - 01/2019
5	Azacitidine (5 Azacytidine)FDA Link 01/2021 - 01/2010
4	Lenalidomide (CC 5013)FDA Link 01/2021 - 01/2014
2	isocitric acid (isocitrate)IBA 04/2020 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 11/2019 - 06/2014
2	cc-486IBA 01/2019 - 01/2015
2	CytidineIBA 02/2010 - 01/2010
2	Decitabine FDA Link 02/2010 - 01/2010
1	venetoclaxIBA 01/2022
1	Arginine (L-Arginine)FDA Link 01/2019
1	pembrolizumabIBA 01/2019
1	alpha-hydroxyglutarateIBA 12/2018
1	Protein Isoforms (Isoforms)IBA 12/2018
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 12/2018
1	HematinicsIBA 01/2016
1	NucleosidesIBA 02/2010

Therapy/Procedure

2	Therapeutics 01/2021 - 04/2020
1	Drug Therapy (Chemotherapy) 11/2019